Updated April 29, 2026
Agno (formerly Phidata) is an open-source Python framework for building production-grade AI agents and multi-agent systems. 39K+ GitHub stars, 23+ LLM providers supported, 100+ pre-built tool integrations, MCP-compatible. Includes AgentOS — a stateless FastAPI runtime — and a control plane UI for monitoring.
CrewAI is a framework for orchestrating multi-agent AI systems where specialized agents collaborate to complete complex tasks. It provides abstractions for defining agent roles, goals, tools, and workflows, enabling teams of AI agents to work together like a human crew. CrewAI supports sequential, parallel, and hierarchical task execution patterns and integrates with all major LLM providers.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
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Agno has emerged as one of the fastest-growing AI agent frameworks in 2026 — 39,100+ stars and a 424-contributor community.
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Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.