Updated March 10, 2026
AutoGen is Microsoft's open-source framework for building multi-agent AI systems. It enables the creation of conversational agents that can work together, use tools, and interact with humans to solve complex tasks. AutoGen supports customizable agent behaviors, flexible conversation patterns, and integrations with various LLMs. The framework is popular for building research assistants, coding agents, and automated analysis pipelines.
Google's Agent Development Kit (ADK) is a modular framework for building AI agents that integrates natively with Gemini models and Vertex AI. It supports multi-agent architectures, tool use, memory, and deployment to Google Cloud, providing an end-to-end solution for building agents in the Google ecosystem.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
Pros
Cons
Pros
Cons
Choose AutoGen if you wantChoose if you want
Choose Google ADK if you wantChoose if you want
Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.