Updated April 29, 2026
Hermes Agent is Nous Research's open-source autonomous AI agent with persistent memory across sessions. Released February 2026; hit 95.6K GitHub stars in seven weeks. Memory persists in ~/.hermes/memories/ plus 8 external provider plugins (Mem0, Honcho, OpenViking, etc.). Self-creates skills that compound over months of use.
Mastra is a TypeScript-first agent framework for building production AI applications. It provides primitives for agents, workflows, RAG, integrations, and memory with a focus on developer experience and type safety. Mastra is designed for full-stack TypeScript developers who want to build AI features without leaving their existing tech stack.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
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Released February 2026; seven weeks later it hit 95,600 GitHub stars — the fastest-growing agent framework of 2026.
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Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.