Updated April 29, 2026
Open WebUI is the de-facto self-hosted AI chat platform — a feature-rich, extensible web UI that runs entirely offline and supports Ollama, OpenAI-compatible APIs, MCP servers, RAG with 9+ vector databases, voice I/O, and multi-user RBAC. 124K+ GitHub stars, 282M+ downloads.
Relevance AI is a no-code platform for building AI agents and automations for business teams. It provides a visual builder for creating multi-step AI workflows that can search data, generate content, analyze documents, and integrate with business tools. Relevance AI is designed for GTM teams who want to deploy AI agents for sales, marketing, and operations tasks.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
Pros
Cons
Pros
Cons
Adds everything Ollama's CLI lacks — conversation history, file uploads for document chat, web search, multi-user accounts, voice I/O, and a lot more.
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Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.