CalypsoAI: AI Security

Founded 2018|Dublin, Ireland|51-200 people

What is CalypsoAI?

CalypsoAI is a pioneering AI security company founded in 2018 that provides the only full-lifecycle platform to secure AI agents and applications at the inference layer. Headquartered in Dublin, Ireland with operations in New York, CalypsoAI has established itself as a leader in enterprise AI security through its innovative 'Agentic Warfare' approach to protecting organizations from evolving AI threats. The company's technology deploys a comprehensive 'test–defend–observe' stack that protects applications, APIs, models, and agents throughout the AI lifecycle.

CalypsoAI has earned significant industry recognition, including being a Top-Two Finalist in the 2025 RSAC Innovation Sandbox contest and one of Fast Company's Most Innovative Companies in AI for 2025. The company secured over USD 40 million in venture funding from prominent investors including Paladin Capital Group, Lockheed Martin Ventures, and Hakluyt Capital, demonstrating strong confidence in its security-first approach to AI.

In September 2025, F5 Networks acquired CalypsoAI for USD 180 million, positioning F5 as the first major vendor to embed comprehensive AI-native security directly into application delivery infrastructure. CalypsoAI's technology is trusted by global enterprises including Palantir and SGK, and the acquisition enables F5 to integrate CalypsoAI's enterprise-ready security capabilities into the F5 Application Delivery and Security Platform, providing enhanced protection for AI-powered applications at scale.

Strengths and tradeoffs

What this tool does well, and the limitations to keep in mind.

Pros

Only full-lifecycle platform for AI security at inference layer
Strong industry recognition including RSAC Innovation Sandbox finalist
Trusted by major enterprises like Palantir and SGK
USD 180M F5 acquisition validates technology and market position

Cons

Enterprise-only pricing may be prohibitive for smaller organizations
Complex security features require expertise to implement
Now owned by F5, which may change product direction

Plans & pricing

What's included in each plan, and how the tiers compare.

Enterprise

Custom

Annual contract

Full-lifecycle AI security
Inference layer protection
Test-defend-observe stack
Application and API security
Model and agent protection
Dedicated support
SLA guarantees

View official pricing page

Using CalypsoAI with Respan

Integrate CalypsoAI's enterprise AI security platform with Respan to add comprehensive protection to your AI workflows. Secure your AI agents and applications at the inference layer with CalypsoAI's test-defend-observe approach. Through Respan's platform, you can ensure that all AI interactions are protected against evolving threats while maintaining performance and reliability.

Protect AI applications with full-lifecycle security
Secure inference layer against adversarial attacks
Monitor and defend AI agents with real-time threat detection
Maintain compliance with enterprise security standards

Run CalypsoAI in production with Respan

10KFree traces/mo

1,000+Models

5 minSetup

Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 1,000+ models through one gateway.

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Best CalypsoAI alternatives & competitors

Top companies in AI Security you can use instead of CalypsoAI.

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