Updated April 29, 2026
Agno (formerly Phidata) is an open-source Python framework for building production-grade AI agents and multi-agent systems. 39K+ GitHub stars, 23+ LLM providers supported, 100+ pre-built tool integrations, MCP-compatible. Includes AgentOS — a stateless FastAPI runtime — and a control plane UI for monitoring.
Llama Stack is Meta's standardized API and SDK for building AI applications on top of Llama models. It provides a unified interface for inference, safety, memory, and agentic workflows — with swappable providers for local, cloud, and on-device deployment. As the official framework for the Llama ecosystem, it is becoming the default for teams building on open-source Llama models.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
Pros
Cons
Pros
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Agno has emerged as one of the fastest-growing AI agent frameworks in 2026 — 39,100+ stars and a 424-contributor community.
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Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.