Updated April 29, 2026
AutoGen is Microsoft's open-source framework for building multi-agent AI systems. It enables the creation of conversational agents that can work together, use tools, and interact with humans to solve complex tasks. AutoGen supports customizable agent behaviors, flexible conversation patterns, and integrations with various LLMs. The framework is popular for building research assistants, coding agents, and automated analysis pipelines.
LangGraph is LangChain's graph-based orchestration framework for stateful, multi-step AI agents. Workflows are modeled as directed graphs with nodes and edges, supporting cycles, conditional routing, and durable state. v1.0 released in 2026 with full enterprise certifications. Used in production by Uber, JPMorgan, BlackRock, and Cisco.
Core capabilities each platform advertises.
What each tool does well, and the limitations to keep in mind.
Pros
Cons
Pros
Cons
LangGraph and AutoGen are the only two frameworks with full enterprise certifications as of 2026. LangChain and LangGraph have 90M monthly downloads and power production at Uber, JPMorgan, BlackRock, and Cisco.
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Respan lets you trace LLM and agent calls across any model or framework, A/B test prompts on production traffic, and route requests across 500+ models through one gateway.